Autism and Vaccines

The CDC is now spreading misinformation not supported by the research

On November 19, 2025, under orders from HHS Secretary, RFK Jr, the CDC modified its webpage discussing Vaccines and Autism by adding asterisk to the header, “Vaccines do not cause Autism”. The goal of the asterisk was to negate the claim of the header. (An annotated version of that webpage is included at the bottom of this document.)

The evidence below indicates that this asterisk is based on dangerous misinformation based on a repeatedly discredited version assertion about links between vaccines and autism

  • The rise in autism is primarily if not entirely an artifact of changes in the disease definition and improved detection of autism.
  • The relationship between trends in autism diagnoses and increases in childhood vaccinations is not consistent with causality.
  • There is strong evidence that the MMR (Measles, Mumps, Rubella) vaccine does NOT cause.autism.
  • There is no evidence that any other childhood vaccine causes autism.

Consider each

The rise in autism prevalence since the 1980s correlates with the rise in the
number of vaccines given to infants

CDC, 11/19/2025

Bottom Line:

The evidence below shows:

  • The number of people diagnosed with autism has risen dramatically, but this is primarily, if not exclusively, a shift in the way we define and detect the condition.
  • THERE IS NO AUTISM EPIDEMIC.

Key Facts

  • Autism did not exist as a DSM diagnostic category until 1980.
  • Diagnostic criteria expanded in 1987, 1994, and 2000.
  • “On the spectrum” became formalized with the creation of Autism Spectrum Disorder in 2013.
  • No objective biomarker exists; diagnosis is inherently subjective.
  • “Failure to adjust for diagnostic drift renders trend comparisons meaningless.”

The Experts Weigh In

Johns Hopkins School of Public Health

“There are two main reasons for the increase. The first is the broadened definition of Autism Spectrum Disorder, which means that more people are meeting this definition now than previously. 

Second, there have been many widely successful public health programs that increased screening at wellness visits for children ages 18–24 months to look for signs of autism. Parents, caregivers, and community members are also more aware of the symptoms, and autism is being more accepted in the community. People are not as afraid to seek help and know where to go when they have concerns. “

The data has shown that rates of autism for that subgroup have increased minimally, if at all, over the past nearly 10 years. “

 Christine Ladd-Acosta, PhD, vice director of the Wendy Klag Center for Autism and Developmental Disabilities at Johns Hopkins University


Harvard School of Public Health

” …the codification of autism in the DSM-III in 1980 and the subsequent inclusion of Asperger’s syndrome in the DSM-IV in 1994 (later to be combined into a single autism spectrum disorder diagnosis in the DSM-5 in 2013) would lead to substantial increases in autism diagnosis.”
– Ari Ne’eman, Harvard School of Public Healthhttps://www.statnews.com/2025/09/30/rfk-jr-autism-diagnosis-epidemic-ussr-jfk-delegation/


Key References

Shattuck, P. T. The Contribution of Diagnostic Substitution to the Growing Administrative Prevalence of Autism in US Special Education. Pediatrics 117, 1028–1037 (2006).

“Prevalence findings from special education data do not support the claim of an autism epidemic because the administrative prevalence figures for most states are well below epidemiological estimates. The growing administrative prevalence of autism from 1994 to 2003 was associated with corresponding declines in the usage of other diagnostic categories.”

The rise in autism was matched by a decline in other, similar diagnoses.

Adamou, M. et al. Enhancing Adult Autism Diagnostic Pathways: The Role of Clinical Triage in Efficient Service Provision. J Clin Med 14, 2933 (2025).

The Autism Service “received a total of 985 referrals for autism diagnostic assessment. The Autism Service accepted 185 referrals for triage. The remaining cohort of referrals was deemed clinically inappropriate and was not triaged for assessment.”
The study involved detailed evaluations of 60 patients not accepted for triage.
“None of the evaluation cases resulted in a clinical diagnosis of ASD”

Primary care doctors tend to over diagnose autism.

Arvidsson, O. et al. ASD and ADHD symptoms in 18-year-olds – A population-based study of twins born 1993 to 2001. Psychiatry Research 351, 116613 (2025).

“The rise in clinical diagnoses of [Autism Spectrum Disorder] in the adolescent/young adult population does not seem to be paralleled by a similar increase in ASD symptoms.”

An objective assessment of trends in the symptoms of autism found NO rise in those symptoms during a period of dramatic increases in the numbers of reported cases

Issue 2: The Trend Lines

Bottom Line

Both curves are rising for unrelated reasons. The relationship between the curves argues AGAINST a causal relationship


The Timeline Problem

Even if some of the rise in the diagnosis of autism did reflect an increase in disease, if vaccines were responsible, autism diagnoses would change in predictable ways following major vaccine introductions.

They don’t.

Key Facts

  • Polio vaccine (1960) → no change in autism diagnoses
  • MMR vaccine (1971) → no change
  • Autism diagnoses rise only after 1980, following DSM shifts
  • Vaccines increase in steps; autism diagnoses rise smoothly
  • No vaccine schedule change corresponds with any inflection in autism prevalence

Interpretation:
The curves conflict.
This is extremely weak evidence of an association.

“In fact, there are still no studies that support the claim that any of the 20 doses of the seven infant vaccines… do not cause autism.” – CDC Page

Bottom Line

This framing demands the impossible: proof of a universal negative. Science does not produce “proof of no effect.”, it evaluates hypotheses using available evidence.
Many studies have looked at this association and found NO evidence to support a link between vaccines and autism.

The Evidence Base

  • More than 1,200 studies
  • 10 meta-analyses
  • 8 Institute of Medicine reports
  • AHRQ systematic review

The Experts Weigh In

American Academy of Pediatrics

“Multiple studies from around the world have found no credible link between autism and vaccines. Continuing to push this false science poses significant risks to public health, particularly during one of the worst measles outbreaks in decades. It is also hurtful to the autistic community and a disservice to the thousands of autistic children and adults living rich, fulfilling lives.”
— Kristin Sohl, MD, FAAP


Key References

The revised CDC website cites these reports — then ignores their conclusions.

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